Madrid have a 25-4 advantage with one draw from 30 previous matches against Rayo Vallecano.
Now Los Blancos have also won three of the last four meetings and picked up a 2-1 home victory in a La Liga fixture back in May.
Jude Bellingham continues to be the shining light for Real Madrid with his El Clasico brace taking his tally to 10 La Liga goals this season.